Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753485 | 0.89 | MEN1 (0.38) | SCN9ALMNARENMEN1KMT2A | |
| SCHEMBL4292768 | 0.89 | MEN1 (0.38) | SCN9ALMNARENMEN1KMT2A | |
| SCHEMBL4752929 | 0.89 | CCR3 (0.39) | SCN9ALMNAREN | |
| SCHEMBL4290277 | 0.89 | CCR3 (0.39) | SCN9ALMNAREN | |
| Hydrochloric Acid SCHEMBL4289621 | 0.89 | LMNA (0.48) | ALDH1A1KDM4ELMNATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL4290984 | 0.88 | SCN9A (0.38) | ALDH1A1SCN9AKDM4ERENMEN1 | |
| SCHEMBL4290889 | 0.83 | KDM4E (0.43) | ALDH1A1KDM4ERENMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4290963 | 0.82 | KDM4E (0.43) | ALDH1A1TP53KDM4ERENMEN1 | |
| Hydrochloric Acid SCHEMBL4290259 | 0.82 | HTR2C (0.40) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL4292929 | 0.82 | HPGD (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885TP53 2535/4885SCN9A 1866/4885 |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885TP53 2535/4885SCN9A 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.