Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986552 | 0.86 | SLC1A3 (0.70) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| SCHEMBL2677967 | 0.86 | SLC1A3 (0.70) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| SCHEMBL2037306 | 0.86 | SLC1A3 (0.70) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| Hydrochloric Acid SCHEMBL6751263 | 0.85 | SLC1A3 (0.69) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| Hydrochloric Acid SCHEMBL29025567 | 0.85 | SLC1A3 (0.69) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5652476 | 0.85 | SLC1A3 (0.69) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| Lysine SCHEMBL4185576 | 0.84 | SLC1A3 (0.56) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| SCHEMBL3362561 | 0.84 | DPP8 (0.50) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| SCHEMBL22133069 | 0.84 | DPP8 (0.50) | SLC1A3SLC1A1HTTDPP8DPP7 | |
| SCHEMBL7758995 | 0.84 | DPP8 (0.50) | SLC1A3SLC1A1HTTDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250121067-A1 | WATER-SOLUBLE CANNABINOID PRODRUGS COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME | TRAIT BIOSCIENCES INC (US) | 2025-04-17 | — | — | US | disclosed |
| US-20090299061-A1 | FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY | PENN STATE RESEARCH FOUNDATION | 2009-12-03 | — | — | US | disclosed |
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-20050147997-A1 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2005-07-07 | — | — | US | disclosed |
| WO-2005047245-A2 | FLUORESCENCE ASSAYS WITH IMPROVED BLOCKING GROUPS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050147997-A1 | Fluorescence assays with improved sensitivity | UACA, HNRNPUL1, FUS | SLC1A3 3677/4885SLC1A1 4091/4885HTT 2179/4885 |
| US-20250121067-A1 | WATER-SOLUBLE CANNABINOID PRODRUGS COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME | CNR2, CNR1, BSG | SLC1A3 20/4885SLC1A1 25/4885HTT 1806/4885 |
| US-20090299061-A1 | FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY | UACA, HNRNPUL1, FUS | SLC1A3 3677/4885SLC1A1 4091/4885HTT 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.