SCHEMBL4282620

SCHEMBL4282620

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(CCBr)cc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 10/20 0.64
▸ MAPT P10636 3/20 0.64
▸ HPGD P15428 2/20 0.64
▸ MEN1 O00255 2/20 0.64
▸ HTT P42858 2/20 0.64
▸ KMT2A Q03164 2/20 0.64
▸ CYP2C19 P33261 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ BLM P54132 1/20 0.64
▸ SMAD3 P84022 1/20 0.64
▸ PRMT1 Q99873 1/20 0.64
▸ ACE2 Q9BYF1 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.64
▸ GSTP1 P09211 1/20 0.50
▸ ALOX12 P18054 2/20 0.46
▸ ALDH1A1 P00352 2/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ BRCA1 P38398 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27584257 0.92 FTO (0.63) FTOMAPTHPGDMEN1HTT
SCHEMBL29755003 0.90 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL337558 0.90 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL7599409 0.89 FTO (0.66) FTOMAPTHPGDMEN1HTT
SCHEMBL22772907 0.86 FTO (0.69) FTOMAPTHPGDMEN1HTT
SCHEMBL14498109 0.85 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL329252 0.85 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL2334255 0.85 FTO (0.70) FTOMAPTHPGDMEN1HTT
SCHEMBL30249984 0.85 FTO (0.70) FTOMAPTHPGDMEN1HTT
SCHEMBL27833470 0.84 FTO (0.83) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1398301-B Method for labeling nucleic acid BIO MERIEUX 2011-03-23 — — CN claimed
US-20090149332-A1 METHODS FOR DETERMINING THE ACTIVITY OF ADAM-TS PROTEASES USING THIOPEPTOLIDES SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2009-06-11 — — US claimed
CN-101018801-A Method for labeling and purifying nucleic acids of interest present in a biological sample to be treated in a single reaction vessel BIOMERIEUX SA (FR) 2007-08-15 — — CN claimed
CN-1325659-C Method for labelling and fragmenting DNA BIO MERIEUX (FR) 2007-07-11 — — CN claimed
CN-1639356-A Method for labelling and fragmenting DNA BIO MERIEUX (FR) 2005-07-13 — — CN claimed
CN-1398301-A Method for labeling nucleic acid BIO MERIEUX (FR) 2003-02-19 — — CN claimed
CN-101679452-B Marking reagents bearing diazo and nitro functions, methods for the synthesis of such reagents and methods for detecting biological molecules BIOMERIEUX (FR) 2014-10-01 — — CN disclosed
CN-103717586-A Benzodioxepine and benzodioxine compounds that interact with glucokinase regulatory protein for the treatment of diabetes AMGEN INC 2014-04-09 — — CN disclosed
CN-102216472-A Rna detection method RIBOXX GMBH 2011-10-12 — — CN disclosed
CN-102112443-A Marker reagents with a pyridine ring with a diazomethyl function substituent methods for synthesis of said reagents and methods for detecting biological molecules BIOMERIEUX SA 2011-06-29 — — CN disclosed
CN-102007221-A Methods for detection of a target nucleic acid by forming a cleavage structure with a cleavage resistant probe STRATAGENE INC 2011-04-06 — — CN disclosed
CN-1398301-B Method for labeling nucleic acid BIO MERIEUX 2011-03-23 — — CN disclosed
CN-101707886-A Methods and compositions for the detection of a nucleic acid by a cleavage reaction STRATAGENE CALIFORNIA 2010-05-12 — — CN disclosed
CN-1463292-A Method for analyzing polynucleotide VARY GENIX CORP (US) 2003-12-24 — — CN disclosed
CN-1398301-A Method for labeling nucleic acid BIO MERIEUX (FR) 2003-02-19 — — CN disclosed
CN-1391616-A Method for labeling ribonucleic acid and labeled RNA fragment obtained thereby BIO MERIEUX (FR) 2003-01-15 — — CN disclosed
US-5705649-A USING (7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO ALKANOIC ACID DERIVATIVE FLUORESCENT DYES PROMEGA CORPORATION (US) 1998-01-06 — — US disclosed
EP-0558658-A4 — — 1994-08-31 — — EP disclosed
EP-0558658-A1 PROTEIN STAINING COMPOSITIONS AND METHODS PROMEGA CORPORATION (US) 1993-09-08 — — EP disclosed
WO-1992008689-A1 PROTEIN STAINING COMPOSITIONS AND METHODS PROMEGA CORPORATION (US) 1992-05-29 — — WO disclosed
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