Sugi Predict

Sugi Predict / Compounds / SCHEMBL7599409

SCHEMBL7599409

SCHEMBL7599409

[O]CCc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 10/20 0.66
▸ MAPT P10636 3/20 0.66
▸ HPGD P15428 2/20 0.66
▸ MEN1 O00255 2/20 0.66
▸ HTT P42858 2/20 0.66
▸ KMT2A Q03164 2/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ RECQL P46063 1/20 0.66
▸ BLM P54132 1/20 0.66
▸ SMAD3 P84022 1/20 0.66
▸ PRMT1 Q99873 1/20 0.66
▸ ACE2 Q9BYF1 1/20 0.66
▸ TDP1 Q9NUW8 1/20 0.66
▸ GSTP1 P09211 1/20 0.51
▸ ALOX12 P18054 2/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ BRCA1 P38398 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4282620 0.89 FTO (0.64) FTOMAPTHPGDMEN1HTT
SCHEMBL22772907 0.87 FTO (0.69) FTOMAPTHPGDMEN1HTT
SCHEMBL2334255 0.86 FTO (0.70) FTOMAPTHPGDMEN1HTT
SCHEMBL29755003 0.86 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL30249984 0.86 FTO (0.70) FTOMAPTHPGDMEN1HTT
SCHEMBL329252 0.86 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL337558 0.86 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL14498109 0.86 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL27833470 0.85 FTO (0.83) FTOMAPTHPGDMEN1HTT
Bromide SCHEMBL6999393 0.85 FTO (0.69) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6124478-A Methods of using 1,2-dioxetanes and kits therefore TROPIX, INC. (US) 2000-09-26 — — US claimed
US-6417380-B1 POLYCYCLOALKYL KETONE CONTAINING FLUORESCENT CHROMOPHORE IS ALKYLATED TO POLYCYCLOALKYLIDENE ETHER IN PRESENCE OF ALKALI METAL ALKOXIDE IN POLAR APROTIC SOLVENT APPLIED BIOSYSTEMS, LLC 2002-07-09 — — US disclosed
US-6124478-A Methods of using 1,2-dioxetanes and kits therefore TROPIX, INC. (US) 2000-09-26 — — US disclosed
EP-0582317-B1 Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX INC (US) 1999-08-25 — — EP disclosed
US-5856522-A Method of using synthesis of 1,2-dioxetanes and kits therefore TROPIX, INC. (US) 1999-01-05 — — US disclosed
US-5777133-A Synthesis of 1, 2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1998-07-07 — — US disclosed
US-5648555-A Alkenes APPLIED BIOSYSTEMS, LLC 1997-07-15 — — US disclosed
US-5639907-A Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1997-06-17 — — US disclosed
US-5637747-A Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1997-06-10 — — US disclosed
US-5625077-A 1,2-dioxetanes TROPIX, INC. (US) 1997-04-29 — — US disclosed
EP-0582317-A2 Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1994-02-09 — — EP disclosed
US-5177241-A SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR APPLIED BIOSYSTEMS, LLC 1993-01-05 — — US disclosed
US-4956477-A Synthesis of 1,2-dioxetanes TROPIX, INC. (US) 1990-09-11 — — US disclosed
EP-0368946-A1 1,2-DIOXETANES. QUEST SYSTEMS INC (US) 1990-05-23 — — EP disclosed
EP-0368946-A4 1,2-DIOXETANES. QUEST SYSTEMS INC (US) 1990-05-14 — — EP disclosed
WO-1989006226-A1 SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR QUEST SYSTEMS, INC. (US) 1989-07-13 — — WO disclosed