SCHEMBL4282675

SCHEMBL4282675

CC(C)Oc1ccc(C(=O)c2c(O)cc(CO)cc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.47
KMT2A Q03164 1/20 0.44
POLB P06746 1/20 0.41
NR1H4 Q96RI1 1/20 0.38
F10 P00742 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SRD5A2 P31213 1/20 0.38
FFAR4 Q5NUL3 6/20 0.37
TRPV1 Q8NER1 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4290549 0.89 PARP10 (0.46) PARP10KMT2APOLBNR1H4F10
SCHEMBL4292523 0.85 PARP10 (0.43) PARP10KMT2APOLBMAOB
SCHEMBL4287006 0.85 NFKB1 (0.46) PARP10KMT2ANPC1HPGDRAB9A
SCHEMBL4279729 0.83 KDM4E (0.49) PARP10KMT2ANPC1HPGDRAB9A
SCHEMBL4280994 0.83 PARP10 (0.50) PARP10KMT2APOLBNPC1HPGD
SCHEMBL4287058 0.81 SLC5A1 (0.48) NPC1RAB9ASMN1; SMN2MAOB
SCHEMBL27746671 0.73 SLC5A1 (0.47) PARP10KMT2ANPC1HPGDRAB9A
SCHEMBL2517350 0.72 KMT2A (0.73) PARP10KMT2APOLBNPC1HPGD
SCHEMBL4279702 0.71 NFKB1 (0.45) KMT2ANPC1HPGDRAB9ASMN1; SMN2
SCHEMBL19002750 0.71 KMT2A (0.61) PARP10KMT2APOLBNPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 PARP10 2557/4885KMT2A 1397/4885POLB 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.