SCHEMBL4279729

SCHEMBL4279729

CCOc1ccc(C(=O)c2c(O)cc(CO)cc2F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
MAPT P10636 2/20 0.49
ALOX15 P16050 2/20 0.49
HPGD P15428 2/20 0.49
ALDH1A1 P00352 2/20 0.49
RECQL P46063 1/20 0.49
HSD17B10 Q99714 1/20 0.49
PARP10 Q53GL7 1/20 0.48
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
SLC5A1 P13866 2/20 0.46
SLC5A2 P31639 2/20 0.46
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAOB P27338 3/20 0.43
NPC1 O15118 2/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4287058 0.90 SLC5A1 (0.48) MAPTSLC5A1SLC5A2LMNAMAPK1
SCHEMBL27746671 0.90 SLC5A1 (0.47) KDM4EMAPTALOX15HPGDALDH1A1
SCHEMBL4287006 0.86 NFKB1 (0.46) MAPTHPGDALDH1A1PARP10KMT2A
SCHEMBL4279710 0.85 MAOB (0.48) KDM4EMAPTALOX15HPGDALDH1A1
SCHEMBL4279712 0.84 KDM4E (0.49) KDM4EMAPTALOX15HPGDALDH1A1
SCHEMBL4292209 0.84 MAPT (0.51) KDM4EMAPTALOX15HPGDALDH1A1
SCHEMBL4282675 0.83 PARP10 (0.47) HPGDPARP10KMT2AMAOBNPC1
SCHEMBL4294582 0.79 SLC5A1 (0.47) MAPTSLC5A1SLC5A2LMNAL3MBTL1
SCHEMBL27746720 0.77 SLC5A1 (0.48) MAPTSLC5A1SLC5A2LMNAL3MBTL1
SCHEMBL4284273 0.76 SLC5A1 (0.47) KDM4EMAPTALDH1A1KMT2ASLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 KDM4E 1987/4885MAPT 2884/4885ALOX15 4342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.