Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25C | P30307 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5184189 | 0.96 | TSHR (0.67) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| Acetic Acid SCHEMBL4244149 | 0.95 | TSHR (0.65) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| SCHEMBL21986981 | 0.93 | TSHR (0.62) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| SCHEMBL16672525 | 0.90 | TSHR (0.62) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| SCHEMBL16674272 | 0.88 | TSHR (0.65) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| SCHEMBL9969538 | 0.88 | TSHR (0.65) | TSHRALDH1A1HSD17B10TBXAS1SMN1; SMN2 | |
| SCHEMBL29141053 | 0.88 | TSHR (0.65) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| SCHEMBL1073658 | 0.88 | ALDH1A1 (0.71) | TSHRALDH1A1HSD17B10HCRTR1TBXAS1 | |
| SCHEMBL28974979 | 0.87 | TSHR (0.74) | TSHRALDH1A1HSD17B10TBXAS1SMN1; SMN2 | |
| SCHEMBL6464181 | 0.87 | HCRTR1 (0.62) | TSHRALDH1A1HSD17B10HCRTR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 905 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260002924-A1 | METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2026-01-01 | — | — | US | claimed |
| US-20250387365-A1 | Combination Treatment Of Arthritic Disease | SYNACT PHARMA APS (DK) | 2025-12-25 | — | — | US | claimed |
| US-20250302804-A1 | RESOMELAGON AND ITS DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASE, HYPERTENSION AND ATHEROSCLEROSIS | SYNACT PHARMA APS (DK) | 2025-10-02 | — | — | US | claimed |
| EP-4598834-A1 | SYSTEMS AND METHODS FOR CARRIER SYSTEMS FOR CONTROLLED RELEASE DELIVERY IN PERISHABLE GOODS | RYP LABS, Inc. (US) | 2025-08-13 | — | — | EP | claimed |
| EP-4119140-B1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES IN COMBINATION WITH METHOTREXATE FOR USE IN THE TREATMENT OF ARTHRITIC DISEASE | SYNACT PHARMA APS (DK) | 2025-06-25 | — | — | EP | claimed |
| WO-2025124760-A1 | TREATMENT OF SUBPOPULATION OF PATIENTS WITH RHEUMATOID ARTHRITIS | SYNACT PHARMA APS (DK) | 2025-06-19 | — | — | WO | claimed |
| EP-4522160-A1 | RESOMELAGON AND ITS DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASE, HYPERTENSION AND ATHEROSCLEROSIS | SynAct Pharma ApS (DK) | 2025-03-19 | — | — | EP | claimed |
| US-12240925-B2 | Process for preparing solid catalyst components for olefin polymerization | W. R. GRACE & CO.- CONN. (US) | 2025-03-04 | — | — | US | claimed |
| US-20250032449-A1 | TREATMENT OF RHEUMATOID ARTHRITIS | SYNACT PHARMA APS (DK) | 2025-01-30 | — | — | US | claimed |
| EP-4477693-A1 | METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS | Korea Research Institute of Chemical Technology (KR) | 2024-12-18 | — | — | EP | claimed |
| US-7153803-B2 | High activity and good hydrogen response Ziegler-Natta polyethylene catalyst | ENGELHARD CORPORATION (US) | 2006-12-26 | — | — | US | claimed |
| WO-2006012111-A1 | HIGH ACTIVITY AND GOOD HYDROGEN RESPONSE ZIEGLER-NATTA POLYETHYLENE CATALYST | ENGELHARD CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| US-20050288460-A1 | High activity and good hydrogen response Ziegler-Natta polyethylene catalyst | W. R. GRACE & CO.-CONN. | 2005-12-29 | — | — | US | claimed |
| US-5156686-A | Treating with carboxylic acid, conversion to water soluble salt, removing entrained oil in aqueous phase | UNION OIL COMPANY OF CALIFORNIA (US) | 1992-10-20 | — | — | US | claimed |
| US-5037905-A | Process for reducing polymer build-up in heat exchangers during polymerization of alpha-olefins | UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) | 1991-08-06 | — | — | US | claimed |
| EP-0431626-A1 | Process for reducing polymer build-up in heat exchangers during polymerization of alpha-olefins | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1991-06-12 | — | — | EP | claimed |
| US-4978722-A | VAPOR PHASE POLYMERIZATION USING COORDINATION CATALYSTS AND CARBOXYLIC OR PHOSPHORUS ESTERS, AMINES OR AMIDES | MITSUBISHI KASEI CORPORATION (JP) | 1990-12-18 | — | — | US | claimed |
| US-4970187-A | Catalyst for producing an olefin polymer | MITSUBISHI KASEI CORPORATION (JP) | 1990-11-13 | — | — | US | claimed |
| US-4902761-A | Method for producing an olefin polymer | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | claimed |
| US-4404341-A | TITANIUM SOLID, ORGANOALUMINUM COMPOUND | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240925-B2 | Process for preparing solid catalyst components for olefin polymerization | POF1B, PPOX, OGFOD1 | TSHR 3339/4885ALDH1A1 3703/4885HSD17B10 1770/4885 |
| US-20250032449-A1 | TREATMENT OF RHEUMATOID ARTHRITIS | MTX1, MTX2, SYVN1 | TSHR 858/4885ALDH1A1 988/4885HSD17B10 1705/4885 |
| US-20260002924-A1 | METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS | FGB, NR4A1, CYP2E1 | TSHR 4120/4885ALDH1A1 105/4885HSD17B10 193/4885 |
| US-20250302804-A1 | RESOMELAGON AND ITS DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASE, HYPERTENSION AND ATHEROSCLEROSIS | AGT, REN, EDNRB | TSHR 4003/4885ALDH1A1 3532/4885HSD17B10 1233/4885 |
| US-20250387365-A1 | Combination Treatment Of Arthritic Disease | ME1, SUCNR1, CPS1 | TSHR 3269/4885ALDH1A1 344/4885HSD17B10 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.