Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328373 | 0.76 | TRPV4 (0.47) | — | |
| SCHEMBL10448699 | 0.71 | ALDH1A1 (0.71) | ALDH1A1TP53POLBSMN1; SMN2KMT2A | |
| SCHEMBL10448232 | 0.70 | ALDH1A1 (1.00) | ALDH1A1TP53POLBSMN1; SMN2MAPK1 | |
| SCHEMBL10519776 | 0.69 | ALDH1A1 (0.51) | ALDH1A1TP53POLBSMN1; SMN2MAPK1 | |
| SCHEMBL24019594 | 0.67 | TP53 (0.72) | ALDH1A1TP53POLBMAPK1KMT2A | |
| SCHEMBL7934631 | 0.66 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL7934367 | 0.66 | ALDH1A1 (0.54) | ALDH1A1TP53POLBSMN1; SMN2MAPK1 | |
| SCHEMBL21641941 | 0.66 | CYP11B1 (0.40) | — | |
| SCHEMBL8827928 | 0.66 | TP53 (1.00) | ALDH1A1TP53POLBKMT2AMEN1 | |
| SCHEMBL2530213 | 0.65 | EGLN2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923385-B1 | Iridium complex, carbazole derivatives and copolymer having the same | KWANGJU INST SCI & TECH (KR) | 2009-05-27 | — | — | EP | claimed |
| EP-1923385-A1 | Iridium complex, carbazole derivatives and copolymer having the same | Gwangju Institute of Science and Technology (KR) | 2008-05-21 | — | — | EP | claimed |
| EP-1923385-B1 | Iridium complex, carbazole derivatives and copolymer having the same | KWANGJU INST SCI & TECH (KR) | 2009-05-27 | — | — | EP | disclosed |
| EP-1923385-A1 | Iridium complex, carbazole derivatives and copolymer having the same | Gwangju Institute of Science and Technology (KR) | 2008-05-21 | — | — | EP | disclosed |