SCHEMBL4283121

SCHEMBL4283121

CCC(=O)OC(=O)c1cc(=O)[nH]c(=O)[nH]1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
GPR84 Q9NQS5 5/20 0.57
LMNA P02545 2/20 0.52
ALDH1A1 P00352 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 2/20 0.39
HSD17B10 Q99714 3/20 0.39
TSHR P16473 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA1 P00915 1/20 0.38
KDM4E B2RXH2 2/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11841644 0.85 CYP1A2 (0.71) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL28111982 0.83 CYP1A2 (0.69) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL11884800 0.83 CYP1A2 (0.56) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL11042365 0.82 CYP1A2 (0.68) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL917082 0.81 GPR84 (0.68) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL13725275 0.79 GPR84 (0.48) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL2269068 0.79 CYP1A2 (0.62) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL12258154 0.78 LMNA (0.59) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL118496 0.78 CYP1A2 (1.00) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2
SCHEMBL1561426 0.77 CYP1A2 (0.49) CYP1A2GPR84LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009074498-A1 MEDICAL USE OF 3- (2, 2, 2-TRIMETHYLHYDRAZINIXM) PROPIONATE OROTATE GRINDEKS (LV) 2009-06-18 WO disclosed
EP-1667960-B1 MELDONIUM SALTS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS GRINDEKS JSC (LV) 2008-02-13 EP disclosed
EP-1667960-A1 MELDONIUM SALTS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS "Joint Stock Company Grindeks" (LV) 2006-06-14 EP disclosed
WO-2005012233-A8 MELDONIUM SALTS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS GRINDEKS JSC (LV) 2005-05-19 WO disclosed
WO-2005012233-A1 MELDONIUM SALTS, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS 'JOINT STOCK COMPANY GRINDEKS' (LV) 2005-02-10 WO disclosed