Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.79 |
| ▸ | LIG1 | P18858 | 1/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723219 | 0.88 | PKM (1.00) | PKMLIG1HPGDMEN1POLB | |
| SCHEMBL593023 | 0.82 | MEN1 (0.65) | HPGDMEN1POLBRAB9AKMT2A | |
| SCHEMBL2615881 | 0.80 | MEN1 (0.63) | HPGDMEN1POLBRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL9447525 | 0.80 | MEN1 (0.63) | HPGDMEN1POLBRAB9AKMT2A | |
| SCHEMBL2615879 | 0.80 | MEN1 (0.63) | HPGDMEN1POLBRAB9AKMT2A | |
| SCHEMBL16200702 | 0.79 | PLAU (0.48) | PKMLIG1HPGDPLAUALDH1A1 | |
| Hydrochloric Acid SCHEMBL9447603 | 0.78 | MEN1 (0.61) | HPGDMEN1POLBRAB9AKMT2A | |
| SCHEMBL3012845 | 0.76 | KDM4E (0.61) | PKMLIG1HPGDMEN1POLB | |
| SCHEMBL3192220 | 0.75 | PKM (0.53) | PKMLIG1MEN1POLBRAB9A | |
| SCHEMBL6258470 | 0.75 | RAB9A (0.64) | PKMLIG1HPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137789-A1 | Oligonucleotide Probes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137789-A1 | Oligonucleotide Probes | NCL, RNGTT, NSUN3 | PKM 4270/4885LIG1 288/4885HPGD 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.