Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776197 | 0.86 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| SCHEMBL14899045 | 0.84 | AKR1C1 (0.48) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| SCHEMBL27742158 | 0.84 | AKR1C1 (0.48) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| SCHEMBL11098333 | 0.84 | MEN1 (0.47) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| Hydrogen Peroxide SCHEMBL11527807 | 0.78 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| SCHEMBL28148652 | 0.77 | SLC6A4 (0.67) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL27742157 | 0.77 | AKR1C1 (0.42) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| SCHEMBL8655542 | 0.77 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2HDAC4AKR1C1 | |
| SCHEMBL27671441 | 0.76 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL30751157 | 0.76 | CYP19A1 (0.40) | SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | SLC6A4 986/4885SLC6A3 1698/4885SLC6A2 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.