Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517380 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521364 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3517022 | 0.80 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL16205160 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL16298324 | 0.80 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL4283830 | 0.77 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1607 | 0.75 | SLC6A4 (0.90) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3516278 | 0.75 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL13253956 | 0.75 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521991 | 0.75 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394847-B | Cycloalkylamines as monoamine reuptake inhibitors | 塞普拉柯公司 | 2017-05-24 | — | — | CN | disclosed |