Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929473 | 0.84 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2NPC1MAPT | |
| SCHEMBL4578358 | 0.84 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2NPC1MAPT | |
| SCHEMBL13661591 | 0.84 | MAPT (0.70) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL5822282 | 0.84 | CA12 (0.58) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL25803770 | 0.82 | CA12 (0.56) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL84849 | 0.82 | ALDH1A1 (0.57) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL20249046 | 0.82 | CA12 (0.56) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL18629170 | 0.82 | CA12 (0.56) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL27259214 | 0.82 | SIGMAR1 (0.56) | ALDH1A1TDP1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL7131820 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |