Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cicloprofen SCHEMBL30578072 | 1.00 | PTGS2 (0.56) | PTGS2OPRK1PDE4DSRD5A2AKR1C3 | |
| SCHEMBL28794469 | 0.89 | SRD5A2 (0.53) | PTGS2OPRK1PDE4DSRD5A2KMT2A | |
| Flurbiprofen SCHEMBL9090260 | 0.88 | AKR1C3 (0.76) | PTGS2AKR1C3AKR1C2PTGS1MEN1 | |
| SCHEMBL12726876 | 0.87 | AKR1B1 (0.54) | PTGS2OPRK1PDE4DSRD5A2AKR1C3 | |
| SCHEMBL11680879 | 0.84 | HSD17B1 (0.54) | PTGS2OPRK1PDE4DAKR1C3AKR1C2 | |
| SCHEMBL11853759 | 0.84 | PTGS1 (0.52) | PTGS2OPRK1PDE4DAKR1C3AKR1C2 | |
| SCHEMBL11150857 | 0.84 | PTGS2 (0.60) | PTGS2OPRK1PDE4DAKR1C3AKR1C2 | |
| Cicloprofen SCHEMBL10428015 | 0.82 | CYP1A2 (0.47) | PTGS2OPRK1PDE4DSRD5A2AKR1C3 | |
| SCHEMBL4447825 | 0.82 | PTGS1 (0.63) | PTGS2OPRK1PDE4DAKR1C3AKR1C2 | |
| Cicloprofen SCHEMBL11060470 | 0.81 | PTGS2 (0.46) | PTGS2OPRK1PDE4DSRD5A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3308 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50218-E1 | Non-steroidal anti-inflammatory ophthalmic compositions | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2024-11-26 | — | — | US | claimed |
| WO-2024153111-A1 | LIPID CONJUGATES, LIPID NANOPARTICLES AND METHODS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2024-07-25 | — | — | WO | claimed |
| EP-4335413-A2 | PROSTHETIC TISSUE VALVES | Cormatrix Cardiovascular, Inc. (US) | 2024-03-13 | — | — | EP | claimed |
| WO-2023212179-A2 | THERAPEUTIC COMPOSITIONS FOR SKIN DISORDERS AND WOUND REPAIR | UNIVERSITY OF MIAMI (US) | 2023-11-02 | — | — | WO | claimed |
| US-20220110979-A1 | FIBROBLAST REGENERATIVE CELLS | FIGENE, LLC | 2022-04-14 | — | — | US | claimed |
| EP-3908297-A1 | FIBROBLAST REGENERATIVE CELLS | Figene, LLC (US) | 2021-11-17 | — | — | EP | claimed |
| EP-3279663-B1 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | BRIGHAM & WOMENS HOSPITAL INC (US) | 2021-07-28 | — | — | EP | claimed |
| WO-2020146874-A1 | FIBROBLAST REGENERATIVE CELLS | FIGENE, LLC (US) | 2020-07-16 | — | — | WO | claimed |
| EP-3279663-A1 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | The Brigham and Women's Hospital, Inc. (US) | 2018-02-07 | — | — | EP | claimed |
| US-20170281724-A9 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-10-05 | — | — | US | claimed |
| EP-0205215-B1 | PROCESS FOR THE PREPARATION OF 2-ARYLPROPIONIC ACIDS | GIST-BROCADES N.V. (NL) | 1990-08-08 | — | — | EP | claimed |
| EP-0374602-A1 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-06-27 | — | — | EP | claimed |
| US-4886750-A | STEREOSELECTIVE HYDROLYSIS USING MICROORGANISMS | GIST-BROCADES N.V. (NL) | 1989-12-12 | — | — | US | claimed |
| EP-0338852-A1 | Process for the carbonylation of arylalkyl halides | HOECHST CELANESE CORPORATION (US) | 1989-10-25 | — | — | EP | claimed |
| EP-0274146-A1 | Process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1988-07-13 | — | — | EP | claimed |
| EP-0233656-A1 | Microbial esterase and process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1987-08-26 | — | — | EP | claimed |
| CN-86103879-A | Provide the method for 2-arylpropionic acid for oneself | — | 1987-04-08 | — | — | CN | claimed |
| EP-0205215-A2 | Process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1986-12-17 | — | — | EP | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| US-4185100-A | CORTICOSTEROID AND A HYDROTROPIC ACID DERIVATIVE, ENZYME INHIBITORS | JOHNSON & JOHNSON (US) | 1980-01-22 | — | — | US | claimed |