SCHEMBL4284041

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13569701	0.92	CACNA1I (0.55)	CACNA1ICACNA1HCACNA1GKCNH2CCR2
	SCHEMBL4280554	0.92	CACNA1I (0.64)	CACNA1ICACNA1HCACNA1GKCNH2CACNA1B
	SCHEMBL26082029	0.88	CACNA1H (0.60)	CACNA1ICACNA1HCACNA1GKCNH2CCR2
	SCHEMBL4271512	0.88	CACNA1I (0.59)	CACNA1ICACNA1HCACNA1GKCNH2CCR2
	SCHEMBL4276609	0.88	CACNA1I (0.72)	CACNA1ICACNA1HCACNA1GKCNH2
	SCHEMBL4282288	0.87	CCR2 (0.59)	CACNA1ICACNA1HCACNA1GKCNH2CCR2
	SCHEMBL4276850	0.86	CACNA1I (0.61)	CACNA1ICACNA1HCACNA1GKCNH2CCR2
	SCHEMBL4277343	0.85	KCNH2 (0.54)	CACNA1ICACNA1HCACNA1GKCNH2CCR2
	SCHEMBL4271022	0.85	CACNA1I (0.56)	CACNA1ICACNA1HCACNA1GKCNH2
	SCHEMBL4274643	0.85	CACNA1H (0.77)	CACNA1ICACNA1HCACNA1GKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.