SCHEMBL4284350

SCHEMBL4284350

CC(=O)OCCc1ccc(Cc2c(C)cc(C)cc2O)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.40
YWHAG P61981 1/20 0.40
THRA P10827 3/20 0.39
THRB P10828 3/20 0.39
TYR P14679 1/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TNKS2 Q9H2K2 1/20 0.36
RAD52 P43351 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MET P08581 1/20 0.35
IGF1R P08069 1/20 0.35
ALOX15 P16050 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4000887 0.84 L3MBTL1 (0.52) APPTYRL3MBTL1NPC1MAPT
SCHEMBL334275 0.78 APP (0.51) APPYWHAGTYRTNKS2RAD52
SCHEMBL4283210 0.78 BACE1 (0.47) THRATHRBCA1CA2IGF1R
SCHEMBL13034096 0.77 RAD52 (0.46) TNKS2RAD52RAB9ASMN1; SMN2
SCHEMBL4004274 0.77 TDP1 (0.47) TYRL3MBTL1NPC1RAB9A
SCHEMBL6299900 0.76 THRA (0.49) THRATHRBIGF1RALOX15NPC1
SCHEMBL8652676 0.76 LMNA (0.45) RAD52L3MBTL1NPC1MAPTRAB9A
SCHEMBL27653318 0.76 TNKS2 (0.44) TNKS2RAD52METRAB9ASMN1; SMN2
SCHEMBL5613913 0.75 APP (0.68) APPYWHAGMETIGF1RALOX15
SCHEMBL12117745 0.75 CNR1 (0.44) APPYWHAGTNKS2RAD52ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 APP 4216/4885YWHAG 3256/4885THRA 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.