Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | MMP3 | P08254 | 5/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252411 | 0.94 | FFAR1 (0.65) | MMP2FFAR1ABCB1HPGDABCG2 | |
| SCHEMBL2346349 | 0.93 | FFAR1 (0.62) | MMP2FFAR1ABCB1HPGDABCG2 | |
| SCHEMBL2780802 | 0.87 | ALOX15 (0.71) | FFAR1ALOX15MAPT | |
| SCHEMBL5867303 | 0.85 | FFAR1 (0.54) | MMP2FFAR1ALOX15PTGDR2MAPT | |
| SCHEMBL5867304 | 0.85 | FFAR1 (0.54) | MMP2FFAR1ALOX15PTGDR2MAPT | |
| SCHEMBL8377835 | 0.83 | MMP2 (0.55) | MMP2FFAR1ALOX15PTGDR2MAPT | |
| SCHEMBL16380470 | 0.83 | MMP2 (1.00) | MMP2ABCB1HPGDABCG2MMP3 | |
| SCHEMBL2181587 | 0.82 | FFAR1 (0.59) | MMP2FFAR1ABCB1HPGDABCG2 | |
| SCHEMBL1285747 | 0.81 | MMP2 (0.85) | MMP2FFAR1MMP3MMP1MMP9 | |
| SCHEMBL9100540 | 0.81 | PTPN7 (0.63) | MMP2FFAR1KDM4EALOX15PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585983-B2 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK, GMBH (DE) | 2009-09-08 | — | — | US | disclosed |
| US-7585983-B2 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK, GMBH (DE) | 2009-09-08 | — | — | US | disclosed |
| US-20040227128-A1 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
| EP-1440974-A2 | Alkylenedioxythiophenes and Poly(alkylendioxythiophenes) with mesogenic groups | Bayer Chemicals AG (DE) | 2004-07-28 | — | — | EP | disclosed |
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |