SCHEMBL4284627

SCHEMBL4284627

CSCCC(N)C(=O)NC(CO)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
FNTA P49354 4/20 0.45
FNTB P49356 4/20 0.45
PGGT1B P53609 3/20 0.45
TGFBR1 P36897 2/20 0.43
CA2 P00918 2/20 0.43
CA1 P00915 1/20 0.43
MME P08473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4284629 1.00 LMNA (0.48) LMNAFNTAFNTBPGGT1BTGFBR1
SCHEMBL29630632 0.97 LMNA (0.46) LMNAFNTAFNTBPGGT1BTGFBR1
SCHEMBL30575172 0.95 LMNA (0.48) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL29350482 0.93 LMNA (0.43) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL30642092 0.92 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL31438607 0.90 PDCD1LG2 (0.42) LMNAFNTAFNTBPGGT1BTGFBR1
SCHEMBL29630436 0.90 MME (0.45) LMNAFNTAFNTBPGGT1BMME
SCHEMBL1157691 0.90 LMNA (0.57) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL1157690 0.90 LMNA (0.57) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL17823046 0.90 LMNA (0.57) LMNAFNTAFNTBPGGT1BCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794640-B1 METHOD FOR RECOMBINANT PRODUCTION OF LABYRINTHOPEPTINS AND FUNCTIONAL DERIVATIVES THEREOF SANOFI SA (FR) 2016-07-20 EP disclosed
US-20150274787-A1 METHOD FOR RECOMBINANT PRODUCTION OF LABYRINTHOPEPTINS AND FUNCTIONAL DERIVATIVES THEREOF SANOFI (FR) 2015-10-01 US disclosed
EP-2794640-A2 METHOD FOR RECOMBINANT PRODUCTION OF LABYRINTHOPEPTINS AND FUNCTIONAL DERIVATIVES THEREOF SANOFI (FR) 2014-10-29 EP disclosed
WO-2013092672-A2 METHOD FOR RECOMBINANT PRODUCTION OF LABYRINTHOPEPTINS AND FUNCTIONAL DERIVATIVES THEREOF SANOFI (FR) 2013-06-27 WO disclosed
EP-2607374-A1 Method for recombinant production of labyrinthopeptins and functional derivatives thereof SANOFI (FR) 2013-06-26 EP disclosed
EP-1861417-B1 DIMERIC OR MULTIMERIC MICROPROTEINS BIONTECH AG (DE) 2013-05-15 EP disclosed
US-8258258-B2 Dimeric or multimeric microproteins BIONTECH AG (DE) 2012-09-04 US disclosed
US-20090156476-A1 Dimeric or Multimeric Microproteins NASCACELL TECHNOLOGIES AG (DE) 2009-06-18 US disclosed
EP-1861417-A2 DIMERIC OR MULTIMERIC MICROPROTEINS NascaCell Technologies AG (DE) 2007-12-05 EP disclosed
WO-2006094813-A2 DIMERIC OR MULTIMERIC MICROPROTEINS NASCACELL TECHNOLOGIES AG. (DE) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274787-A1 METHOD FOR RECOMBINANT PRODUCTION OF LABYRINTHOPEPTINS AND FUNCTIONAL DERIVATIVES THEREOF THOP1, VIP, PRSS12 LMNA 3517/4885FNTA 247/4885FNTB 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.