Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224522 | 0.77 | MAPK1 (0.39) | HPGDALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL17916235 | 0.75 | HSP90AA1 (0.56) | HPGDALDH1A1HSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL9616143 | 0.74 | ALDH1A1 (0.46) | HPGDALDH1A1HSD17B10BCL2L1HSP90AA1 | |
| SCHEMBL9784010 | 0.73 | NOTUM (0.37) | MAOAIDO1BLMPMP22TSHR | |
| SCHEMBL28988268 | 0.71 | ALDH1A1 (0.50) | HPGDALDH1A1HSD17B10BCL2L1KMT2A | |
| SCHEMBL28574 | 0.71 | ALDH1A1 (0.67) | HPGDALDH1A1HSD17B10BCL2L1KMT2A | |
| SCHEMBL30442890 | 0.71 | ALDH1A1 (0.67) | HPGDALDH1A1HSD17B10BCL2L1KMT2A | |
| SCHEMBL29623192 | 0.71 | ALDH1A1 (0.67) | HPGDALDH1A1HSD17B10BCL2L1KMT2A | |
| SCHEMBL27659427 | 0.71 | ALDH1A1 (0.67) | HPGDALDH1A1HSD17B10BCL2L1KMT2A | |
| SCHEMBL4284888 | 0.70 | HSD17B1 (0.45) | ALDH1A1HSD17B10ESR2LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176307-A1 | Compounds, Compositions and Methods | CYTOKINETICS, INC. | 2009-07-09 | — | — | US | disclosed |