SCHEMBL4285203

SCHEMBL4285203

N[C@@H](Cc1ccc(-c2ccc(/N=N/c3ccccc3)cc2)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.64
PTGS1 P23219 2/20 0.64
ALPI P09923 1/20 0.64
PKM P14618 1/20 0.64
XIAP P98170 1/20 0.64
TPH1 P17752 6/20 0.53
NOS3 P29474 2/20 0.51
NOS1 P29475 2/20 0.51
NOS2 P35228 2/20 0.51
SRR Q9GZT4 2/20 0.49
PSAT1 Q9Y617 2/20 0.49
PTPN1 P18031 1/20 0.48
GRB2 P62993 1/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19368127 0.95 SLC7A5 (0.70) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL12272708 0.95 SLC7A5 (0.70) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL5286259 0.95 SLC7A5 (0.70) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL4338268 0.95 SLC7A5 (0.70) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1712908 0.95 SLC7A5 (0.70) SLC7A5PTGS1ALPIPKMXIAP
Azobenzene SCHEMBL23038628 0.90 SLC7A5 (0.79) SLC7A5PTGS1ALPIPKMXIAP
Azobenzene SCHEMBL8497483 0.88 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL414363 0.87 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL93494 0.87 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL180272 0.87 SLC7A5 (0.78) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710559-A Variant sucrose osmotic enzyme polypeptides 因比奥斯公司 2023-09-05 CN disclosed
CN-104672307-B A kind of method for improving cation small peptide antibiotic property and stability 吉林大学 2017-09-29 CN disclosed
US-20090181858-A1 Adding photoregulated amino acids to the genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2009-07-16 US disclosed
EP-1797177-A4 ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE SCRIPPS RESEARCH INST (US) 2008-07-09 EP disclosed
EP-1797177-A2 ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE The Scripps Research Institute (US) 2007-06-20 EP disclosed
US-20060134746-A1 Adding photoregulated amino acids to the genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2006-06-22 US disclosed
WO-2006034410-A2 ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE THE SCRIPPS RESARCH INSTITUTE (US) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060134746-A1 Adding photoregulated amino acids to the genetic code NSUN3, OSGEP, AARS1 SLC7A5 398/4885PTGS1 2688/4885ALPI 3442/4885
US-20090181858-A1 Adding photoregulated amino acids to the genetic code NSUN3, OSGEP, AARS1 SLC7A5 372/4885PTGS1 2689/4885ALPI 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.