SCHEMBL4285500

SCHEMBL4285500

CO[C@H]1O[C@H](COC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@](C)(OC)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SSTR1 P30872 1/20 0.39
▸ SSTR2 P30874 1/20 0.39
▸ SSTR4 P31391 1/20 0.39
▸ SSTR3 P32745 1/20 0.39
▸ SSTR5 P35346 1/20 0.39
▸ BCHE P06276 4/20 0.36
▸ GJB2 P29033 1/20 0.32
▸ NT5E P21589 1/20 0.31
▸ PTPN2 P17706 2/20 0.31
▸ PTPN1 P18031 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285498 0.87 SSTR1 (0.39) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL31421507 0.78 SSTR1 (0.57) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL4284513 0.74 SSTR1 (0.40) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL18101907 0.73 KIF11 (0.33) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL10409434 0.71 HTR1A (0.44) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL10409432 0.71 HTR1A (0.44) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL22393051 0.71 BCHE (0.42) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL13088350 0.71 SSTR1 (0.46) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL5336247 0.70 ALDH1A1 (0.42) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL338986 0.69 CYP3A4 (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 — — US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 SSTR1 610/4885SSTR2 456/4885SSTR4 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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