Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547697 | 0.84 | ALDH1A1 (0.51) | ERN1KMT2AMEN1LMNATHRB | |
| SCHEMBL4285512 | 0.84 | MEN1 (0.44) | PDK2ERN1KMT2AMEN1LMNA | |
| SCHEMBL1484113 | 0.79 | LMNA (0.52) | ERN1KMT2AMEN1LMNATHRB | |
| Benzene SCHEMBL28952313 | 0.77 | LMNA (0.50) | ERN1KMT2AMEN1LMNATHRB | |
| SCHEMBL10415655 | 0.77 | LMNA (0.50) | ERN1KMT2AMEN1LMNATHRB | |
| SCHEMBL10414731 | 0.77 | LMNA (0.50) | ERN1KMT2AMEN1LMNATHRB | |
| SCHEMBL8120539 | 0.76 | ERN1 (0.57) | ERN1KMT2AMEN1LMNATHRB | |
| SCHEMBL976750 | 0.75 | LMNA (0.52) | ERN1KMT2AMEN1LMNATHRB | |
| SCHEMBL28215494 | 0.74 | ERN1 (0.45) | ERN1KMT2AMEN1LMNATHRB | |
| Hydrochloric Acid SCHEMBL29912876 | 0.74 | ERN1 (0.55) | ERN1KMT2AMEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088444-A1 | Substituted phenanthrene diketo acids and uses therefor | BUOLAMWINI JOHN K | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088444-A1 | Substituted phenanthrene diketo acids and uses therefor | WEE1, WEE2, HADHB | PDK2 39/4885ERN1 1988/4885KMT2A 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.