SCHEMBL4285531

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8373050	0.89	CCR2 (0.58)	KMT2AMEN1CACNA1IHDAC3HDAC4
	SCHEMBL4277469	0.88	CACNA1I (0.68)	CACNA1IHDAC3HDAC4HDAC1HDAC7
	SCHEMBL4272386	0.87	KMT2A (0.64)	KMT2AMEN1L3MBTL1CACNA1IHDAC3
	SCHEMBL14706526	0.87	HDAC3 (0.53)	KMT2AMEN1CACNA1IHDAC3HDAC4
	SCHEMBL4273314	0.86	CACNA1I (0.67)	KMT2AMEN1CACNA1IHDAC3HDAC4
	SCHEMBL4269070	0.86	ALDH1A1 (0.61)	KMT2ACACNA1IKCNH2CCR2MAPT
	SCHEMBL4273162	0.84	KMT2A (0.59)	KMT2AMEN1CACNA1IHDAC3HDAC4
	SCHEMBL4273482	0.83	CACNA1I (0.49)	KMT2AMEN1CACNA1IHDAC3HDAC4
	SCHEMBL4279336	0.83	MEN1 (0.55)	KMT2AMEN1CACNA1IHDAC3HDAC4
	SCHEMBL4272952	0.82	CACNA1I (0.55)	KMT2AMEN1CACNA1IKCNH2CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.