Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4983491 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ADRB1EGLN3CYP2B6CYP19A1 | |
| SCHEMBL4285903 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ADRB1EGLN3CYP2B6CYP19A1 | |
| SCHEMBL13705096 | 0.82 | GPR119 (0.39) | ALDH1A1CYP19A1 | |
| SCHEMBL3493853 | 0.82 | GPR119 (0.39) | ALDH1A1CYP19A1 | |
| SCHEMBL4290754 | 0.76 | CA1 (0.34) | ADRB1 | |
| SCHEMBL4287716 | 0.76 | EGLN3 (0.39) | ALDH1A1ADRB1EGLN3 | |
| SCHEMBL15005734 | 0.71 | REN (0.42) | ADRB1 | |
| SCHEMBL2011996 | 0.71 | REN (0.42) | ADRB1 | |
| SCHEMBL2418102 | 0.71 | REN (0.42) | ADRB1 | |
| SCHEMBL5096971 | 0.70 | CYP2B6 (0.54) | CYP2B6CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885ADRB1 278/4885EGLN3 1069/4885 |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885ADRB1 278/4885EGLN3 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.