Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284667 | 0.77 | CDK4 (0.43) | PDE2AKDM5BKDM4EALDH1A1KHK | |
| SCHEMBL4283741 | 0.71 | L3MBTL1 (0.41) | PDE2AKDM5BHCAR2KDM4EALDH1A1 | |
| SCHEMBL16787495 | 0.68 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL4287126 | 0.63 | KDM5B (0.42) | KDM5BMEN1KMT2A | |
| SCHEMBL9582021 | 0.60 | HPGD (0.47) | KDM5BALDH1A1 | |
| SCHEMBL4282510 | 0.60 | CASR (0.41) | KDM5BALDH1A1 | |
| SCHEMBL24812797 | 0.59 | MAPT (0.53) | HCAR2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL15470617 | 0.59 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBMAPTTNKS2 | |
| SCHEMBL4369980 | 0.59 | POLB (0.34) | KDM4EPOLBMAPT | |
| SCHEMBL5115571 | 0.59 | ALDH1A1 (0.43) | HCAR2KDM4EALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |