Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.52 |
| ▸ | NOS1 | P29475 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 3/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599983 | 0.87 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL12667853 | 0.87 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL5841281 | 0.82 | KDM4E (0.49) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL4596026 | 0.82 | ELANE (0.43) | TSHRELANE | |
| SCHEMBL28268633 | 0.81 | ELANE (0.42) | TSHRELANEALDH1A1 | |
| SCHEMBL155234 | 0.80 | NOS3 (0.55) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL29750308 | 0.80 | NOS3 (0.55) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL155235 | 0.80 | NOS3 (0.55) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL4595466 | 0.80 | NOS3 (0.55) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL27638622 | 0.79 | ELANE (0.45) | PTGS1KDM4ETSHRBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140030199-A1 | ARTIFICIAL NAIL COMPOSITION | SHOFU INC. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20090258966-A1 | Dental Composition | NIHON UNIVERSITY (JP) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258966-A1 | Dental Composition | DCPS, MMAB, CAD | NOS3 4545/4885NOS1 4658/4885NOS2 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.