Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20048223 | 0.85 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2GBA1TP53ALDH1A1 | |
| SCHEMBL20037063 | 0.81 | EGFR (0.52) | RAB9ASMN1; SMN2GBA1TP53GAA | |
| SCHEMBL4288257 | 0.80 | ALDH1A1 (0.67) | RAB9ASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL4283172 | 0.78 | ALDH1A1 (0.63) | RAB9ASMN1; SMN2TP53ALDH1A1NAMPT | |
| SCHEMBL4281610 | 0.78 | EGFR (0.54) | RAB9ASMN1; SMN2GAANAMPTNPC1 | |
| SCHEMBL3825768 | 0.77 | HPGDS (0.57) | RAB9ASMN1; SMN2GAANAMPTNPC1 | |
| SCHEMBL3667956 | 0.77 | KMT2A (0.69) | RAB9ASMN1; SMN2ALDH1A1GAANAMPT | |
| SCHEMBL23719148 | 0.75 | MAPK10 (0.59) | SMN1; SMN2TP53GAANAMPTEGFR | |
| SCHEMBL4287692 | 0.75 | KMT2A (0.60) | RAB9ASMN1; SMN2TP53ALDH1A1NAMPT | |
| SCHEMBL6963518 | 0.74 | SCD (0.48) | NAMPTEGFRFGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | GSK3B, GSK3A, GSKIP | RAB9A 291/4885SMN1; SMN2 4064/4885GBA1 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.