Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248313 | 0.74 | CA2 (0.39) | KMT2AMEN1ALDH1A1TSHRCA2 | |
| SCHEMBL14587066 | 0.72 | CACNA1G (0.44) | KMT2AMEN1ALDH1A1GAACYP1A2 | |
| SCHEMBL5803864 | 0.72 | CA2 (0.40) | KMT2AKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL11384694 | 0.69 | KDM4E (0.36) | KMT2AMEN1KDM4EUSP2HSD17B10 | |
| SCHEMBL6552953 | 0.67 | KDM4E (0.36) | KMT2AKDM4ETSHRLMNAADORA3 | |
| SCHEMBL5964371 | 0.66 | ALDH1A1 (0.42) | KMT2AMEN1KDM4EUSP2ALDH1A1 | |
| SCHEMBL14876802 | 0.66 | ALDH1A1 (0.42) | KMT2AMEN1KDM4EUSP2ALDH1A1 | |
| SCHEMBL31650964 | 0.64 | ALDH1A1 (0.56) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL28054369 | 0.64 | HRH3 (0.43) | GAACYP1A2CYP2C19 | |
| SCHEMBL22721611 | 0.63 | SMN1; SMN2 (0.41) | KMT2AMEN1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203586-A1 | METHOD FOR AMELIORATING AN INFLAMMATORY SKIN CONDITION | SYNGENTA LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| EP-1758990-A2 | METHOD FOR AMELIORATING AN INFLAMMATORY SKIN CONDITION | Syngenta Limited (GB) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121329-A2 | METHOD FOR AMELIORATING AN INFLAMMATORY SKIN CONDITION | SYNGENTA LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005121328-A2 | METHOD FOR AMELIORATING AN INFLAMMATORY SKIN CONDITION | SYNGENTA LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |