Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.96 |
| ▸ | MAPT | P10636 | 7/20 | 0.96 |
| ▸ | NPC1 | O15118 | 5/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.96 |
| ▸ | LTA4H | P09960 | 5/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.66 |
| ▸ | RELA | Q04206 | 2/20 | 0.66 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.66 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HK1 | P19367 | 1/20 | 0.62 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4433292 | 0.98 | RAB9A (1.00) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL3129591 | 0.91 | LTA4H (1.00) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL1771825 | 0.89 | ALDH1A1 (0.79) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL23610361 | 0.87 | ALDH1A1 (0.83) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL172279 | 0.83 | ALDH1A1 (0.70) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL3174725 | 0.83 | RAB9A (0.68) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| Iodide SCHEMBL6175053 | 0.81 | ALDH1A1 (0.68) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL4986233 | 0.80 | KDM4E (0.73) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL128793 | 0.79 | ALDH1A1 (1.00) | RAB9AMAPTNPC1SMN1; SMN2LTA4H | |
| SCHEMBL430121 | 0.79 | LTA4H (0.83) | RAB9AMAPTNPC1SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640835-B | Method for preparing glycerol triacetate through organic catalysis | 南京工业大学 | 2020-08-21 | — | — | CN | claimed |
| CN-108640835-A | Method for preparing glycerol triacetate through organic catalysis | 南京工业大学 | 2018-10-12 | — | — | CN | claimed |
| EP-4688759-A1 | USP2 INHIBITORS AND METHODS OF USING THE SAME FOR THE TREATMENT OF DISEASES | Icahn School of Medicine at Mount Sinai (US) | 2026-02-11 | — | — | EP | disclosed |
| CN-120081363-A | Preparation method and application of nitrogen-sulfur-boron co-doped graphene composite material for lithium ion battery negative electrode | 唐山北碳科技有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-115466229-B | Para-amidobenzenesulfonyl compound and application thereof | 上海中医药大学 | 2025-01-24 | — | — | CN | disclosed |
| WO-2024211785-A1 | USP2 INHIBITORS AND METHODS OF USING THE SAME FOR THE TREATMENT OF DISEASES | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2024-10-10 | — | — | WO | disclosed |
| US-12036208-B2 | Methods for treating neurodegenerative disorders | ALZHEON, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12036208-B2 | Methods for treating neurodegenerative disorders | ALZHEON, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118084890-A | Isoxazoline-containing pyrazole amide compound as well as preparation method and application thereof | 安徽农业大学 | 2024-05-28 | — | — | CN | disclosed |
| US-20240115557-A1 | INHIBITORS OF RNA-GUIDED NUCLEASES AND USES THEREOF | THE BROAD INSTITUTE, INC. | 2024-04-11 | — | — | US | disclosed |
| CN-117486872-A | Mechanical ball milling synthesis method of aminothiazole compound | 浙江工业大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-1176101-A | N -(4 -aryl -thiazol -2 -yl) -sulphonamide derivatives and their use | HOFFMANN LA ROCHE (CH) | 1998-03-18 | — | — | CN | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| EP-0819681-A2 | N-(4-Aryl-thiazol-2-yl)-sulfonamides and their use | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-21 | — | — | EP | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |
| US-4207233-A | Azo dyes containing a thiazole component | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036208-B2 | Methods for treating neurodegenerative disorders | NLN, CLN6, SNCA | RAB9A 1741/4885MAPT 9/4885NPC1 151/4885 |
| US-20240115557-A1 | INHIBITORS OF RNA-GUIDED NUCLEASES AND USES THEREOF | ZFR, ENDOD1, FEN1 | RAB9A 2468/4885MAPT 3271/4885NPC1 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.