Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | THRB | P10828 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | APAF1 | O14727 | 2/20 | 0.69 |
| ▸ | GSR | P00390 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | RAD52 | P43351 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | CASP6 | P55212 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1756447 | 0.99 | APP (0.67) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL343918 | 0.83 | APP (0.69) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL127316 | 0.82 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL29441543 | 0.82 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL7065218 | 0.81 | APP (0.66) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL6128370 | 0.81 | APP (0.66) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL13295376 | 0.81 | APP (0.59) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL4295288 | 0.81 | APP (0.66) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL4227551 | 0.81 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL30664737 | 0.80 | THRB (1.00) | APPMAPTTHRBMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387631-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
| US-11077210-B2 | Near-infrared fluorescent contrast bioimaging agents and methods of use thereof | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2021-08-03 | — | — | US | disclosed |
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2016-09-15 | — | — | US | disclosed |
| US-8294975-B2 | Automotive rearview mirror assembly | DONNELLY CORPORATION (US) | 2012-10-23 | — | — | US | disclosed |
| US-8278298-B2 | Prophylaxis, therapy of Alzheimer's disease, Pick's disease; administering phenothiazine compound such as methylene blue | WISTA LABORATORIES LTD. (SG) | 2012-10-02 | — | — | US | disclosed |
| EP-1421389-B1 | NEUROFIBRILLARY LABELS | WISTA LAB LTD (SG) | 2012-05-02 | — | — | EP | disclosed |
| US-8164817-B2 | Method of forming a mirrored bent cut glass shape for vehicular exterior rearview mirror assembly | DONNELLY CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-8097615-B2 | Neurofibrillary labels | WISTA LABORATORIES LTD. (SG) | 2012-01-17 | — | — | US | disclosed |
| US-20110045172-A1 | METHOD OF FORMING A MIRRORED BENT CUT GLASS SHAPE FOR VEHICULAR EXTERIOR REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2011-02-24 | — | — | US | disclosed |
| EP-1667947-B1 | METHODS OF 11C -RADIOLABELLING PHENOTHIAZINE AND PHENO THIAZINE-LIKE COMPOUNDS | UNIV ABERDEEN (GB) | 2008-08-20 | — | — | EP | disclosed |
| US-7349144-B2 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070191352-A1 | Inhibition of tau-tau-association | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2007-08-16 | — | — | US | disclosed |
| US-20070184284-A1 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-7202987-B2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| US-20070042295-A1 | Optical data carrier comprising a polymeric network in the information layer | LANXESS DEUTSCHLAND GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-7169733-B2 | Visible light-induced photocatalyst | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2007-01-30 | — | — | US | disclosed |
| EP-0712506-A1 | MUTABLE COMPOSITION AND METHODS OF USE THEREOF | KIMBERLY-CLARK CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004955-A1 | MUTABLE COMPOSITION AND METHODS OF USE THEREOF | KIMBERLY-CLARK CORPORATION (US) | 1995-02-16 | — | — | WO | disclosed |
| US-4338180-A | SURFACE-CHALCOGENATED MOLYBENUM OR TUNGSTEN; SOLAR CELLS | KURARAY CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077210-B2 | Near-infrared fluorescent contrast bioimaging agents and methods of use thereof | CD68, MSR1, CD47 | APP 3590/4885MAPT 3284/4885THRB 2423/4885 |
| US-20220387631-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | CD68, MSR1, CD47 | APP 3590/4885MAPT 3284/4885THRB 2423/4885 |
| US-20070191352-A1 | Inhibition of tau-tau-association | MAPT, PSEN1, PSEN2 | APP 44/4885MAPT 1/4885THRB 1395/4885 |
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | CD68, MSR1, CD47 | APP 3590/4885MAPT 3284/4885THRB 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.