SCHEMBL428824

SCHEMBL428824

Cc1c(CO)ccc(O)c1CO

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
PDCD1 Q15116 2/20 0.39
CD274 Q9NZQ7 2/20 0.39
HPGD P15428 1/20 0.39
KLF10 Q13118 1/20 0.39
PKM P14618 1/20 0.38
LMNA P02545 2/20 0.37
GAA P10253 2/20 0.37
NPC1 O15118 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TYR P14679 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394136 0.82 TYR (0.40) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL31302207 0.82 TYR (0.40) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL3468895 0.81 TYR (0.42) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL15957639 0.79 PDCD1 (0.41) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL27810457 0.79 TYR (0.41) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL30694360 0.79 PDCD1 (0.41) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL4878065 0.79 TRPA1 (0.41) KDM4EALDH1A1HSD17B10HPGDKLF10
SCHEMBL207165 0.78 KDM4E (0.41) KDM4EALDH1A1HSD17B10HPGDKLF10
SCHEMBL13199168 0.77 PDCD1 (0.50) KDM4EALDH1A1HSD17B10PDCD1CD274
SCHEMBL5468115 0.76 KDM4E (0.39) KDM4EALDH1A1HSD17B10HPGDKLF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807324-B2 Photoconductors XEROX CORPORATION (US) 2010-10-05 US claimed
US-20080070136-A1 Photoconductors XEROX CORPORATION 2008-03-20 US claimed
WO-2025047702-A1 COMPOSITION FOR PATTERNING AND USE OF SAME 日産化学株式会社 2025-03-06 WO disclosed
WO-2025047700-A1 COMPOSITION FOR FORMING WAVELENGTH CONVERSION FILM AND USE THEREOF 日産化学株式会社 2025-03-06 WO disclosed
WO-2024024502-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION 日産化学株式会社 2024-02-01 WO disclosed
WO-2024024501-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION 日産化学株式会社 2024-02-01 WO disclosed
WO-2022168732-A1 POSITIVE-ACTING PHOTOSENSITIVE RESIN COMPOSITION 日産化学株式会社 2022-08-11 WO disclosed
US-11194252-B2 Cured film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2021-12-07 US disclosed
US-10669376-B2 Cured film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2020-06-02 US disclosed
US-20190085130-A1 CURED FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2019-03-21 US disclosed
US-8211558-B2 Crosslinked polymer electrolyte and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US disclosed
US-20120021190-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING SILICA COATING FILM, AND APPARATUS AND MEMBER EACH COMPRISING SILICA COATING FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-01-26 US disclosed
US-7807324-B2 Photoconductors XEROX CORPORATION (US) 2010-10-05 US disclosed
US-20090274943-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-05 US disclosed
US-20080070136-A1 Photoconductors XEROX CORPORATION 2008-03-20 US disclosed
EP-1873789-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME Sumitomo Chemical Company, Limited (JP) 2008-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669376-B2 Cured film-forming composition AFF1, KDM1A, KDM7A KDM4E 216/4885ALDH1A1 2110/4885HSD17B10 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.