Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218019 | 0.83 | KDM4E (0.40) | TRPA1KDM4EALDH1A1ESR1ESR2 | |
| SCHEMBL8827947 | 0.83 | ESR1 (0.43) | TRPA1ATMESR1ESR2TP53 | |
| SCHEMBL358550 | 0.82 | GABRA1 (0.36) | TRPA1ATMKDM4EALDH1A1HTR1D | |
| SCHEMBL983528 | 0.81 | ESR1 (0.41) | TRPA1ATMKDM4EALDH1A1ESR1 | |
| SCHEMBL33504 | 0.79 | ALDH1A1 (0.44) | TRPA1ATMKDM4EALDH1A1ESR1 | |
| SCHEMBL30805737 | 0.79 | ALDH1A1 (0.44) | TRPA1ATMKDM4EALDH1A1ESR1 | |
| SCHEMBL428824 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL30274388 | 0.79 | ESR1 (0.40) | KDM4EALDH1A1ESR1ESR2TP53 | |
| SCHEMBL12743251 | 0.77 | KDM4E (0.36) | TRPA1KDM4EALDH1A1ESR1ESR2 | |
| SCHEMBL30945836 | 0.77 | CNR1 (0.41) | TRPA1ATMESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612849-A1 | Improved cumene hydroperoxide concentration process | Borealis AG (AT) | 2013-07-10 | — | — | EP | disclosed |
| CN-101268032-B | Decomposition of cumene hydroperoxide | UOP LLC | 2012-10-03 | — | — | CN | disclosed |
| CN-101268032-A | Decomposition of cumene hydroperoxide | UOP LLC (US) | 2008-09-17 | — | — | CN | disclosed |
| EP-1924543-A2 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1922298-A2 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2008-05-21 | — | — | EP | disclosed |
| EP-1922298-A2 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2008-05-21 | — | — | EP | disclosed |
| US-7335797-B2 | Oxidizing cumene to cumene hydroperoxide in a liquid phase in the presence of an oxidizing agent and of a basic pyridinic resin, the basic resin not releasing inorganic cations to the reaction environment; drastic reduction of dimethylphenolcarbinol byproduct; catalyst does not require a regeneration | EUROTECHNICA DEVELOPMENT & LICENSING S.P.A. (IT) | 2008-02-26 | — | — | US | disclosed |
| WO-2007024570-A3 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007024570-A2 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007024570-A2 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007024572-A2 | DECOMPOSITION OF CUMENE HYDROPEROXIDE | UOP LLC (US) | 2007-03-01 | — | — | WO | disclosed |
| US-7141700-B1 | Decomposition of cumene hydroperoxide | UOP LLC (US) | 2006-11-28 | — | — | US | disclosed |
| US-7141701-B1 | Decomposition of cumene hydroperoxide | UOP LLC (US) | 2006-11-28 | — | — | US | disclosed |
| US-7141701-B1 | Decomposition of cumene hydroperoxide | UOP LLC (US) | 2006-11-28 | — | — | US | disclosed |
| US-20060014985-A1 | Oxidizing cumene to cumene hydroperoxide in a liquid phase in the presence of an oxidizing agent and of a basic pyridinic resin, the basic resin not releasing inorganic cations to the reaction environment; drastic reduction of dimethylphenolcarbinol byproduct; catalyst does not require a regeneration | EUROTECNICA CONTRACTORS & ENGINEERS S.P.A. (IT) | 2006-01-19 | — | — | US | disclosed |
| WO-2003076381-A1 | PROCESS FOR THE SYNTHESIS OF CUMENE HYDROPEROXIDE | EUROTECNICA DEVELOPMENT & LICENSING S.P.A. (IT) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014985-A1 | Oxidizing cumene to cumene hydroperoxide in a liquid phase in the presence of an oxidizing agent and of a basic pyridinic resin, the basic resin not releasing inorganic cations to the reaction environment; drastic reduction of dimethylphenolcarbinol byproduct; catalyst does not require a regeneration | PLPBP, CBR1, POR | TRPA1 706/4885ATM 3786/4885KDM4E 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.