Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288423 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNANR3C2PGRGAA | |
| SCHEMBL8238482 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNANR3C2PGRGAA | |
| SCHEMBL4291344 | 0.89 | NR3C2 (0.48) | NR3C2PGRNR3C1MAPTADRB2 | |
| SCHEMBL8239799 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNANR3C2PGRGAA | |
| SCHEMBL4286827 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNANR3C2PGRGAA | |
| SCHEMBL4286826 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNANR3C2PGRGAA | |
| SCHEMBL4293530 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNANR3C2GAAMAPT | |
| SCHEMBL4286786 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNANR3C2GAAMAPT | |
| SCHEMBL4286793 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNANR3C2GAAMAPT | |
| SCHEMBL13658814 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNANR3C2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253687-A1 | Fused Heterocyclic Compounds and Their Use as Mineralocorticoid Receptor Ligands | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253687-A1 | Fused Heterocyclic Compounds and Their Use as Mineralocorticoid Receptor Ligands | NR3C2, NR3C1, MC2R | ALDH1A1 2708/4885LMNA 2152/4885NR3C2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.