Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4275856 | 0.88 | SCD (0.47) | SCDASIC3 | |
| SCHEMBL3729733 | 0.84 | SCD (0.57) | SCDASIC3HTR2CHTR2B | |
| SCHEMBL4275101 | 0.83 | SCD (0.64) | SCD | |
| Hydrochloric Acid SCHEMBL3725765 | 0.83 | SCD (0.57) | SCDASIC3HTR2CHTR2B | |
| SCHEMBL4289707 | 0.83 | PTGER1 (0.46) | ROCK2 | |
| Hydrochloric Acid SCHEMBL4276243 | 0.83 | SCD (0.63) | SCD | |
| Hydrochloric Acid SCHEMBL4279816 | 0.82 | PTGER1 (0.46) | ROCK2 | |
| SCHEMBL4283514 | 0.80 | WNT1 (0.44) | SCDASIC3ROCK2HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4275852 | 0.79 | WNT1 (0.44) | SCDASIC3ROCK2HTR2CHTR2B | |
| SCHEMBL4283504 | 0.79 | HPGD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150196-A1 | N-THIAZOLYL-1, 2, 3, 4-TETRAHYDRO-6-ISOQUINOLINECARBOXAMIDE DERIVATIVES AS INHIBITORS OF STEAROYL COENZYME A DESATURASE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |