Phenothiazine

Phenothiazine

SCHEMBL4288768

CC(C)(C)c1ccc(O)c(O)c1.c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 1/20 0.58
HSD17B10 Q99714 1/20 0.58
NOX1 Q9Y5S8 11/20 0.52
GAA P10253 8/20 0.52
MAPT P10636 8/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
SNCA P37840 3/20 0.52
BCHE P06276 2/20 0.52
ACHE P22303 2/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
ALOX12 P18054 1/20 0.52
MAOA P21397 1/20 0.52
CNR1 P21554 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL25339417 0.89 ALOX15 (0.45) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL1719191 0.84 NOX1 (0.62) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL25898787 0.84 NOX1 (0.71) ALOX15TDP1ALDH1A1HSD17B10NOX1
Phenothiazine SCHEMBL28572162 0.83 NOX1 (0.57) ALOX15TDP1ALDH1A1NOX1GAA
Phenothiazine SCHEMBL6025548 0.78 NOX1 (0.77) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL29358687 0.76 ALDH1A1 (1.00) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL50705 0.76 ALDH1A1 (1.00) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL30336020 0.75 SNCA (0.50) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL20664930 0.75 SNCA (0.50) ALOX15TDP1ALDH1A1HPGDHSD17B10
SCHEMBL28661434 0.74 ALDH1A1 (0.95) ALOX15TDP1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9377686-B2 Photosensitive resin composition, conductive wire protection film, and touch panel member TORAY INDUSTRIES, INC. (JP) 2016-06-28 US disclosed
US-20150205203-A1 PHOTOSENSITIVE RESIN COMPOSITION, CONDUCTIVE WIRE PROTECTION FILM, AND TOUCH PANEL MEMBER TORAY INDUSTRIES, INC. (JP) 2015-07-23 US disclosed
EP-2871522-A1 PHOTOSENSITIVE RESIN COMPOSITION, CONDUCTIVE WIRE PROTECTION FILM, AND TOUCH PANEL MEMBER Toray Industries, Inc. (JP) 2015-05-13 EP disclosed
CN-104428713-A Photosensitive resin composition, conductive wire protection film, and touch panel member TORAY INDUSTRIES 2015-03-18 CN disclosed
CN-101176033-B Sealing agent for liquid crystal dropping process, vertical conduction material, and liquid crystal display element SEKISUI CHEMICAL CO LTD 2010-05-26 CN disclosed
US-20090061117-A1 Sealant for one drop fill process, vertically conducting material and liquid crystal display device SEKISUI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
CN-101176033-A Sealing agent for liquid crystal dropping process, vertical conduction material, and liquid crystal display element SEKISUI CHEMICAL CO LTD (JP) 2008-05-07 CN disclosed