SCHEMBL4289037

SCHEMBL4289037

CCc1ccc(Cc2ccc(CCO)cc2OCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
LTA4H P09960 1/20 0.43
EPHX2 P34913 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
APP P05067 1/20 0.43
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
BRD4 O60885 1/20 0.41
ABCB1 P08183 2/20 0.40
HTR1A P08908 2/20 0.40
DRD2 P14416 2/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
FFAR1 O14842 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
BLM P54132 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4003289 0.89 ELANE (0.43)
SCHEMBL11844159 0.87 MAPK1 (0.46) ABCB1HTR1ADRD2ABCG2
SCHEMBL4289366 0.87 ABCB1 (0.55) CYP4F2CYP4A11LTA4HEPHX2MTNR1A
SCHEMBL4007795 0.83 SLC22A12 (0.51) FFAR4APPBRD4FFAR1
SCHEMBL6819629 0.82 ELANE (0.47) LTA4HEPHX2HTR1ADRD2
SCHEMBL4285234 0.82 GAA (0.41) APPHTR1AKDM4E
SCHEMBL3998721 0.81 HTT (0.44) FFAR4APPABCB1ABCG2
SCHEMBL4287560 0.81 ALDH1A1 (0.54) FFAR4APPMTNR1AMTNR1BBRD4
SCHEMBL3996516 0.81 MAPK1 (0.40) ABCB1ABCG2CYP1A2CYP3A4CYP2D6
SCHEMBL3999257 0.81 RXRA (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 CYP4F2 531/4885CYP4A11 512/4885LTA4H 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.