SCHEMBL4289366

SCHEMBL4289366

COc1ccc(Cc2ccc(CCO)cc2OCc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 7/20 0.55
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
HTR1A P08908 2/20 0.50
DRD2 P14416 2/20 0.50
LTA4H P09960 2/20 0.49
EPHX2 P34913 1/20 0.48
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
PPARA Q07869 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
MEN1 O00255 1/20 0.44
BCHE P06276 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4283023 0.90 ABCB1 (0.54) ABCB1HTR1ADRD2LTA4HPPARA
SCHEMBL4289037 0.87 CYP4F2 (0.50) ABCB1CYP4F2CYP4A11HTR1ADRD2
SCHEMBL27563776 0.84 MAOB (0.57) ABCB1HTR1ADRD2LTA4HMTNR1A
SCHEMBL4281014 0.82 ABCB1 (0.52) ABCB1HTR1ADRD2LTA4HPPARA
SCHEMBL4284026 0.82 ALDH1A1 (0.51) ABCB1LTA4HMTNR1AMTNR1BPPARA
SCHEMBL4279823 0.81 RAB9A (0.59) ABCB1PPARA
SCHEMBL4284136 0.80 NPC1 (0.59) ABCB1LTA4HMEN1KMT2A
SCHEMBL1322956 0.80 KDM4E (0.64) ABCB1CYP4F2CYP4A11MTNR1AMTNR1B
SCHEMBL12296058 0.80 BCHE (0.61) ABCB1CYP4F2CYP4A11MTNR1AMTNR1B
SCHEMBL6819629 0.80 ELANE (0.47) HTR1ADRD2LTA4HEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 ABCB1 222/4885CYP4F2 531/4885CYP4A11 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.