Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584545 | 1.00 | HRH3 (0.37) | HRH3HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL27786683 | 0.90 | HRH3 (0.35) | HRH3HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL5822210 | 0.80 | HSD17B10 (0.39) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL9013386 | 0.79 | HRH3 (0.35) | HRH3HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL27816157 | 0.74 | HRH3 (0.41) | HRH3HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL21171596 | 0.72 | HRH3 (0.37) | HRH3RECQLCTSKUSP2SMN1; SMN2 | |
| SCHEMBL19889936 | 0.72 | HRH3 (0.37) | HRH3RECQLCTSKUSP2SMN1; SMN2 | |
| SCHEMBL21483550 | 0.71 | GABRR1 (0.42) | HRH3CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL17234602 | 0.71 | GABRR1 (0.42) | HRH3CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL18541279 | 0.71 | GABRR1 (0.42) | HRH3CHRM2CHRM1CHRM3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022100-A1 | ORGANIC COMPOUNDS | MAIBAUM JUERGEN KLAUS (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20090076062-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022100-A1 | ORGANIC COMPOUNDS | AGTR1, AGTR2, REN | HRH3 533/4885HPGD 285/4885CHRM2 1104/4885 |
| US-20090076062-A1 | Organic Compounds | AGTR1, AGTR2, REN | HRH3 533/4885HPGD 285/4885CHRM2 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.