Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275426 | 0.89 | ALOX15 (0.38) | KMT2AALOX15BLMPMP22 | |
| Serine SCHEMBL17199761 | 0.85 | ALOX15 (0.41) | KMT2AALOX15BLMPMP22 | |
| Glutamine SCHEMBL27639978 | 0.84 | KMT2A (0.45) | KMT2AALOX15BLMPMP22MEN1 | |
| Glutamine SCHEMBL1304984 | 0.84 | KMT2A (0.45) | KMT2AALOX15BLMPMP22MEN1 | |
| Glutamine SCHEMBL10610943 | 0.82 | GSR (0.32) | KMT2AALOX15BLMPMP22 | |
| SCHEMBL30716624 | 0.81 | QARS1 (0.40) | BLM | |
| Threonine SCHEMBL4405364 | 0.81 | DPP4 (0.34) | KMT2AMEN1 | |
| Glutamine SCHEMBL28719330 | 0.80 | ALOX15 (0.41) | KMT2AALOX15BLMPMP22 | |
| Glutamine SCHEMBL28801797 | 0.80 | ALOX15 (0.41) | KMT2AALOX15BLMPMP22 | |
| Glutamine SCHEMBL10428556 | 0.80 | ALOX15 (0.41) | KMT2AALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896049-B1 | TRIPEPTIDES THAT DOWN REGULATE THE ACTIVITY OF PLASMA MEMBRANE TRANSPORTERS INCLUDING SODIUM-D-GLUCOSE COTRANSPORTER SGLT1 | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2017-11-29 | — | — | EP | disclosed |
| US-8207133-B1 | Peptides that down regulate the activity of plasma membrane transporters including sodium-D-glucose cotransporter SGLT1 | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) | 2012-06-26 | — | — | US | disclosed |
| US-20120148673-A1 | PEPTIDES THAT DOWN REGULATE THE ACTIVITY OF PLASMA MEMBRANE TRANSPORTERS INCLUDING SODIUM-D-GLUCOSE COTRANSPORTER SGLT1 | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20090203621-A1 | Tripeptides that Down Regulate the Activity of Plasma Membrane transporters Including Sodium-D-Glucose Cotransporter Sglt1 | JULIUS-MAXIMILLIANS-UNIVERSITAT WURZBURG | 2009-08-13 | — | — | US | disclosed |