Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537324 | 0.92 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1537462 | 0.92 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3236621 | 0.85 | NOS2 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| Isoleucine SCHEMBL27660748 | 0.84 | DPP4 (0.37) | DPP4DPP8DPP9DPP7FAP | |
| Isoleucine SCHEMBL4405367 | 0.84 | DPP4 (0.37) | DPP4DPP8DPP9DPP7FAP | |
| Serine SCHEMBL18428172 | 0.82 | ELANE (0.31) | MEN1KMT2A | |
| Threonine SCHEMBL4289282 | 0.81 | KMT2A (0.35) | MEN1KMT2A | |
| SCHEMBL4610559 | 0.80 | CPB2 (0.35) | MEN1KMT2A | |
| Isoleucine SCHEMBL6534831 | 0.80 | DPP4 (0.34) | DPP4DPP8DPP9DPP7FAP | |
| Threonine SCHEMBL9802531 | 0.80 | REN (0.42) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143311-A1 | Compositions comprising tripeptides inhibiting ace | CONOPCO, INC. D/B/A UNILEVER | 2009-06-04 | — | — | US | disclosed |
| US-20090131331-A1 | Novel Nutraceutical Compositions | DSM IP ASSETS B.V. (NL) | 2009-05-21 | — | — | US | disclosed |
| EP-1881841-A1 | COMPOSITIONS COMPRISING TRIPEPTIDES INHIBITING ACE | UNILEVER N.V. (NL) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006114195-A1 | COMPOSITIONS COMPRISING TRIPEPTIDES INHIBITING ACE | UNILEVER N.V. (NL) | 2006-11-02 | — | — | WO | disclosed |