Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25342148 | 0.80 | ALDH1A1 (0.39) | ALDH1A1SLC2A1KDM4EHPGDPARP1 | |
| SCHEMBL12778742 | 0.74 | AXL (0.42) | AXLTRPA1TRPM8TRPV1PDE3B | |
| SCHEMBL24687930 | 0.73 | TIPARP (0.40) | TIPARP | |
| SCHEMBL23336009 | 0.72 | TIPARP (0.42) | ALDH1A1SLC2A1TIPARP | |
| SCHEMBL3658974 | 0.72 | — | — | |
| SCHEMBL1310786 | 0.68 | — | — | |
| SCHEMBL12065687 | 0.68 | — | — | |
| SCHEMBL15633366 | 0.68 | NOTUM (0.43) | ALDH1A1NOTUMGAAKDM4ETP53 | |
| SCHEMBL8162479 | 0.67 | AXL (0.44) | AXLTRPA1NOTUMTRPM8TRPV1 | |
| SCHEMBL30731335 | 0.67 | AXL (0.38) | ALDH1A1AXLTRPA1NOTUMTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1371638-B1 | Pyridazinone derivatives as intermediates of herbicides | SUMITOMO CHEMICAL CO (JP) | 2005-11-16 | — | — | EP | claimed |
| EP-1371638-A1 | Pyridazinone derivatives as intermediates of herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-12-17 | — | — | EP | claimed |
| US-20020026048-A1 | Pyridazinone derivatives | SUMITOMO CHEMICAL CO. LTD. | 2002-02-28 | — | — | US | claimed |
| US-6187920-B1 | HERBICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 2001-02-13 | — | — | US | claimed |
| EP-0947509-A2 | Pyridazinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | claimed |
| US-20190322627-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-10-24 | — | — | US | disclosed |
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026048-A1 | Pyridazinone derivatives | PDXK, DDT, CBR3 | ALDH1A1 105/4885AXL 1362/4885TRPA1 1434/4885 |
| US-20190322627-A1 | AGRICULTURAL CHEMICALS | DDT, DHFR, AS3MT | ALDH1A1 201/4885AXL 3790/4885TRPA1 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.