Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.62 |
| ▸ | CA9 | Q16790 | 13/20 | 0.62 |
| ▸ | CA12 | O43570 | 12/20 | 0.62 |
| ▸ | CA1 | P00915 | 14/20 | 0.59 |
| ▸ | CA5A | P35218 | 8/20 | 0.59 |
| ▸ | CA7 | P43166 | 8/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.59 |
| ▸ | CA6 | P23280 | 6/20 | 0.59 |
| ▸ | CA4 | P22748 | 6/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 3/20 | 0.56 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202948 | 0.85 | CA2 (0.81) | CA2CA9CA12CA1CA5A | |
| SCHEMBL216845 | 0.77 | CA2 (0.64) | CA2CA9CA12CA1CA5A | |
| SCHEMBL10493509 | 0.77 | CA2 (0.68) | CA2CA9CA12CA1CA5A | |
| Sulfanilamide SCHEMBL11751516 | 0.76 | CA2 (0.90) | CA2CA9CA12CA1CA5A | |
| Sulfanilamide SCHEMBL2746422 | 0.76 | CA2 (0.90) | CA2CA9CA12CA1CA5A | |
| Sulfanilamide SCHEMBL30659052 | 0.74 | CA2 (1.00) | CA2CA9CA12CA1CA5A | |
| Sulfanilamide SCHEMBL31544839 | 0.74 | CA2 (1.00) | CA2CA9CA12CA1CA5A | |
| Sulfanilamide SCHEMBL2798899 | 0.74 | CA2 (1.00) | CA2CA9CA12CA1CA5A | |
| Sulfanilamide SCHEMBL740 | 0.74 | CA2 (1.00) | CA2CA9CA12CA1CA5A | |
| SCHEMBL1805283 | 0.74 | CA2 (0.65) | CA2CA9CA12CA1CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066027-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2024-02-29 | — | — | US | claimed |
| EP-4255904-A2 | NOVEL PAR-2 INHIBITORS | Domain Therapeutics (FR) | 2023-10-11 | — | — | EP | claimed |
| WO-2022117882-A2 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2022-06-09 | — | — | WO | claimed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | claimed |
| EP-2791142-B1 | COMPOUNDS AND METHODS FOR THE PREVENTION AND TREATMENT OF TUMOR METASTASIS AND TUMORIGENESIS | US HEALTH (US) | 2019-07-03 | — | — | EP | claimed |
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-02-21 | — | — | US | claimed |
| EP-3429997-A1 | N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2019-01-23 | — | — | EP | claimed |
| CN-109071444-A | N- (cyanobenzyl) -6- (cyclopropyl-carbonylamino) -4- (phenyl) -pyridine-2-carboxamide derivatives and related compounds as pesticides and plant protection agents | 拜耳作物科学股份公司 | 2018-12-21 | — | — | CN | claimed |
| CN-108697719-A | Modulators of extracellular 5' -nucleotidase and uses thereof | 艾库斯生物科学有限公司 | 2018-10-23 | — | — | CN | claimed |
| WO-2018140630-A1 | AUTOPHAGY INDUCERS FOR TREATMENT OF CNS CONDITIONS | NORTHWESTERN UNIVERSITY (US) | 2018-08-02 | — | — | WO | claimed |
| EP-0911030-B1 | Antimicrobial composition comprising a vinyyl pyrrolidinon derivative and a carbapenem antibiotic or a beta-lactamase inhibitor | BASILEA PHARMACEUTICA AG (CH) | 2005-04-13 | — | — | EP | claimed |
| US-6479492-B1 | TREATMENT OF INFLAMMATORY DISEASES IN A MAMMALIAN PATIENT | ELAN PHARMACEUTICALS, INC. | 2002-11-12 | — | — | US | claimed |
| US-6369070-B1 | Methods for inhibiting mrp1 | ELI LILLY AND COMPANY | 2002-04-09 | — | — | US | claimed |
| EP-1067928-A4 | METHODS FOR INHIBITING MRP1 | LILLY CO ELI (US) | 2001-11-14 | — | — | EP | claimed |
| CN-1304306-A | Method for inhibiting MRP1 | LILLY CO ELI (US) | 2001-07-18 | — | — | CN | claimed |
| EP-1067928-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999051228-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | claimed |
| EP-0911030-A2 | Antimicrobial composition comprising a vinyyl pyrrolidinon derivative and a carbapenem antibiotic or a beta-lactamase inhibitor | F.HOFFMANN-LA ROCHE AG (CH) | 1999-04-28 | — | — | EP | claimed |
| EP-0356454-B1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| US-4025622-A | ANTIBACTERIAL | Ogura, Haruo (JA) | 1977-05-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | CHRM1, CHRM2, ACHE | CA2 1370/4885CA9 3063/4885CA12 4356/4885 |
| US-20240066027-A1 | NOVEL PAR-2 INHIBITORS | F2RL1, F2R, F2RL3 | CA2 2401/4885CA9 3574/4885CA12 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.