SCHEMBL4289715

SCHEMBL4289715

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nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.42
PRKCE Q02156 2/20 0.42
PRKCQ Q04759 2/20 0.42
PRKCD Q05655 2/20 0.42
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
ENPEP Q07075 3/20 0.35
ANPEP P15144 2/20 0.35
TLR2 O60603 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026886 0.81 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCD
SCHEMBL4872186 0.79 PTGS1 (0.44) PRKCAPTGS1SLC7A11ENPEPANPEP
SCHEMBL3396294 0.79 PTGS1 (0.44) PRKCAPTGS1SLC7A11ENPEPANPEP
SCHEMBL10130615 0.76 PRKCA (0.65) PRKCAPRKCEPRKCQPRKCD
Succinic Acid SCHEMBL15323069 0.75 PRKCA (0.40) PRKCAPRKCEPRKCQPRKCD
SCHEMBL14181781 0.73 PTGS1 (0.43) PTGS1SLC7A11ENPEPTLR2
Succinic Acid SCHEMBL15323308 0.72 PRKCA (0.40) PRKCAPRKCEPRKCQPRKCDTLR2
SCHEMBL1405394 0.71 LMNA (0.56) PRKCAPRKCEPRKCQPRKCDTLR2
SCHEMBL538145 0.71 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCD
SCHEMBL2790714 0.71 PRKCA (0.49) PRKCAPRKCEPRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090220587-A1 Liposomal drug delivery constructs targeted by lipid-conjugated peptide ligands UNITED STATE ARMY (US) 2009-09-03 US claimed
US-20090220587-A1 Liposomal drug delivery constructs targeted by lipid-conjugated peptide ligands UNITED STATE ARMY (US) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090220587-A1 Liposomal drug delivery constructs targeted by lipid-conjugated peptide ligands LDLR, LAMP2, LAMP1 PRKCA 3265/4885PRKCE 3370/4885PRKCQ 3159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.