Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291531 | 0.90 | SIGMAR1 (0.37) | CA1CA2CA4CA9SIGMAR1 | |
| SCHEMBL4287604 | 0.89 | CA1 (0.36) | CA1CA2CA4CA9ROCK1 | |
| SCHEMBL4284797 | 0.89 | CA1 (0.35) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4289813 | 0.89 | CA1 (0.35) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4281681 | 0.88 | CA1 (0.42) | CA1CA2CA4CA9SIGMAR1 | |
| SCHEMBL4288504 | 0.88 | CA1 (0.36) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4294545 | 0.88 | SIGMAR1 (0.36) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4291276 | 0.88 | SIGMAR1 (0.36) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4295182 | 0.87 | CA1 (0.34) | CA1CA2CA4CA9ROCK1 | |
| SCHEMBL4290876 | 0.87 | ABHD6 (0.35) | CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090214514-A1 | GUS3 NEUROPEPTIDES FOR REGULATING HYPOTHALAMIC FUNCTION | RHEOSCIENCE A/S (DK) | 2009-08-27 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1771193-A1 | GUS3 NEUROPEPTIDES FOR REGULATING HYPOTHALAMIC FUNCTION | Rheoscience A/S (DK) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006007854-A1 | GUS3 NEUROPEPTIDES FOR REGULATING HYPOTHALAMIC FUNCTION | RHEOSCIENCE A/S (DK) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | CA1 2275/4885CA2 218/4885CA4 296/4885 |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | CA1 2275/4885CA2 218/4885CA4 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.