SCHEMBL4291049

SCHEMBL4291049

CNC(=O)N(c1nc(C)nc(OC)n1)S(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP13 P45452 1/20 0.36
FABP4 P15090 5/20 0.35
CA12 O43570 5/20 0.34
CA9 Q16790 5/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5458880 0.92 CA1 (0.42) MEN1KMT2ACA1CA2CA9
SCHEMBL4284694 0.87 F2 (0.42) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL9055616 0.85 ALDH1A1 (0.33) MEN1KMT2AMMP1MMP9MMP13
SCHEMBL7693190 0.81 CA1 (0.43) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL8848745 0.80 CA1 (0.46) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL29368060 0.80 CA1 (0.42) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL66383 0.80 CA1 (0.42) MEN1KMT2AF2PRSS1PRSS2
Tribenuron Methyl SCHEMBL2437168 0.76 MEN1 (0.41) MEN1KMT2ACA1CA2MMP1
SCHEMBL10390488 0.76 CA1 (0.38) MEN1KMT2ACA1CA2CA9
SCHEMBL28553704 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds CORET JOEL M 2008-05-15 US claimed
WO-2006009937-A2 NOVEL ESTERS AS USEFUL BROAD SPECTRUM HERBICIDAL COMPOUNDS CORET JOEL MARCEL (US) 2006-01-26 WO claimed
US-20050282708-A1 Novel esters as useful herbicidal compounds CORET JOEL M 2005-12-22 US claimed
US-20050282706-A1 Novel esters as useful broad spectrum herbicidal compounds CORET JOEL M 2005-12-22 US claimed
EP-0987945-B1 NEW HERBICIDAL MIXTURES AVENTIS CROPSCIENCE SA (FR) 2001-10-24 EP claimed
US-6239070-B1 REDUCING PHYTOTOXICITY USING 4-BENZOYLISOXAZOLE HERBICIDE;MIXTURE CONTAINING PLANT SAFENING AGENT RHONE-POULENC INC. 2001-05-29 US claimed
EP-0987945-A1 NEW HERBICIDAL MIXTURES RHONE-POULENC AGROCHIMIE (FR) 2000-03-29 EP claimed
WO-1998056251-A1 NEW HERBICIDAL MIXTURES RHONE-POULENC AGRO (FR) 1998-12-17 WO claimed
EP-0619946-B1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO LTD (JP) 1996-06-05 EP claimed
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 EP disclosed
CN-111373035-B Rape triazole-resistant pyrimidine sulfonamide herbicide gene and application thereof 江苏省农业科学院 2023-03-28 CN disclosed
CN-109497083-B Medicament for removing flying cotton and fly of plants and application thereof 北京市园林科学研究院 2021-07-30 CN disclosed
EP-3752201-A1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2020-12-23 EP disclosed
CN-111373035-A Rape triazole-resistant pyrimidine sulfonamide herbicide gene and application thereof 江苏省农业科学院 2020-07-03 CN disclosed
US-5561099-A OIL-BASED CHEMICALS OSI SPECIALTIES, INC. (US) 1996-10-01 US disclosed
US-5558806-A ADJUVANT IN PESTICIDE SPRAYS OSI SPECIALTIES, INC. (US) 1996-09-24 US disclosed
EP-0642304-A4 SUPER-SPREADING, LOW-FOAM SURFACTANT FOR AGRICULTURAL SPRAY MIXTURES. OSI SPECIALTIES INC (US) 1995-08-16 EP disclosed
EP-0648413-A1 Alkylsiloxanes as adjuvants for agriculture OSi Specialties, Inc. (US) 1995-04-19 EP disclosed
EP-0642304-A1 SUPER-SPREADING, LOW-FOAM SURFACTANT FOR AGRICULTURAL SPRAY MIXTURES OSi Specialties, Inc. (US) 1995-03-15 EP disclosed
WO-1994022311-A1 SUPER-SPREADING, LOW-FOAM SURFACTANT FOR AGRICULTURAL SPRAY MIXTURES OSI SPECIALTIES, INC. (US) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282708-A1 Novel esters as useful herbicidal compounds NOTUM, DDT, HDHD5 MEN1 4687/4885KMT2A 732/4885F2 4873/4885
US-20050282706-A1 Novel esters as useful broad spectrum herbicidal compounds NOTUM, DDT, HDHD5 MEN1 4725/4885KMT2A 802/4885F2 4865/4885
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds NOTUM, DDT, HDHD5 MEN1 4725/4885KMT2A 802/4885F2 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.