Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.58 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658709 | 0.86 | GUSB (0.67) | ALDH1A1KMT2ALMNATDP1MEN1 | |
| SCHEMBL17805683 | 0.81 | PKM (0.71) | ALDH1A1PKMKMT2ASLC10A6NFKBIA | |
| SCHEMBL16680267 | 0.80 | SMN1; SMN2 (0.67) | ALDH1A1PKMKMT2ALMNAMEN1 | |
| SCHEMBL6343982 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1PKMKMT2ASLC10A6LMNA | |
| SCHEMBL13265815 | 0.80 | AMY1A (0.54) | ALDH1A1KMT2ALMNAMEN1NPC1 | |
| SCHEMBL7451030 | 0.80 | PKM (0.64) | PKMKMT2ASLC10A6NFKBIARELA | |
| SCHEMBL8276485 | 0.80 | KMT2A (0.62) | ALDH1A1PKMKMT2ALMNATDP1 | |
| SCHEMBL2239360 | 0.79 | HPGD (0.74) | ALDH1A1PKMKMT2ALMNATDP1 | |
| SCHEMBL16679842 | 0.79 | GAA (0.55) | ALDH1A1PKMLMNATDP1CA1 | |
| SCHEMBL3780817 | 0.78 | PKM (0.63) | PKMKMT2ASLC10A6NFKBIARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655299-A1 | NEW COMPOUNDS FOR TREATING STAPHYLOCOCCUS INFECTIONS | Ab2 Therapeutics, S. L. (ES) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024156895-A1 | NEW COMPOUNDS FOR TREATING STAPHYLOCOCCUS INFECTIONS | ABAC Therapeutics, S.L. (ES) | 2024-08-02 | — | — | WO | disclosed |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885PKM 847/4885KMT2A 1049/4885 |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885PKM 847/4885KMT2A 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.