Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685558 | 0.98 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL5597442 | 0.64 | CRBN (0.41) | KDM4E | |
| SCHEMBL10761357 | 0.63 | MAPT (0.44) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL25974508 | 0.63 | MAPT (0.44) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL19370610 | 0.63 | OPRM1 (0.40) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL31436228 | 0.63 | MAPT (0.44) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL6236013 | 0.63 | OPRM1 (0.46) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL5004525 | 0.61 | MEN1 (0.38) | MAPT | |
| SCHEMBL6235625 | 0.61 | OPRM1 (0.49) | KDM4EALDH1A1MAPTPKM | |
| SCHEMBL22904415 | 0.60 | OPRM1 (0.39) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009157938-A1 | A2B ADENOSINE RECEPTOR ANTAGONISTS FOR TREATING CANCER | CV THERAPEUTICS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |