Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285496 | 0.71 | TOP2A (0.34) | CRBNKDM4ELMNACYP2C19 | |
| SCHEMBL4284253 | 0.67 | PTGS1 (0.37) | KDM4ELMNACYP2C19 | |
| SCHEMBL14058728 | 0.65 | CYP19A1 (0.34) | — | |
| SCHEMBL4283528 | 0.64 | DDB1 (0.46) | CRBNKDM4ECYP2C19 | |
| SCHEMBL4291499 | 0.64 | KDM4E (0.31) | KDM4E | |
| SCHEMBL5685558 | 0.63 | ALDH1A1 (0.33) | KDM4ELMNACYP2C19 | |
| SCHEMBL24372750 | 0.60 | CRBN (0.50) | CRBNKDM4ELMNACYP2C19TSHR | |
| SCHEMBL10025159 | 0.60 | — | — | |
| SCHEMBL10028354 | 0.60 | — | — | |
| SCHEMBL21769 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799221-A1 | METHOD OF PREVENTING AND TREATING AIRWAY REMODELING AND PULMONARY INFLAMMATION USING A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006044610-A1 | METHOD OF PREVENTING AND TREATING AIRWAY REMODELING AND PULMONARY INFLAMMATION USING A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC (US) | 2006-04-27 | — | — | WO | disclosed |