Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10107580 | 0.77 | SLC6A4 (0.64) | SLC6A4SLC6A2KCNH2HPGDTSHR | |
| SCHEMBL3809371 | 0.75 | SLC6A4 (0.51) | SLC6A4SLC6A2KCNH2HPGDTSHR | |
| SCHEMBL28872695 | 0.75 | SMN1; SMN2 (0.52) | SLC6A4LMNA | |
| Hydrochloric Acid SCHEMBL5782440 | 0.73 | MAOA (0.47) | SLC6A4SLC6A2KCNH2BCAT2SLC6A3 | |
| SCHEMBL3620874 | 0.70 | HPGD (0.56) | HPGDTSHRLMNA | |
| SCHEMBL3619527 | 0.70 | HPGD (0.56) | HPGDTSHRLMNA | |
| SCHEMBL9001760 | 0.70 | TSHR (0.79) | HPGDTSHRLMNA | |
| SCHEMBL5134802 | 0.69 | PARP1 (0.51) | SLC6A4SLC6A2KCNH2SLC6A3 | |
| SCHEMBL672520 | 0.69 | SLC6A4 (0.72) | SLC6A4SLC6A2KCNH2SLC6A3 | |
| SCHEMBL672519 | 0.69 | SLC6A4 (0.72) | SLC6A4SLC6A2KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |