Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884521 | 0.80 | KCNN4 (0.39) | KCNN4CES1MAPK1KIF11KCNH2 | |
| SCHEMBL27360229 | 0.79 | KCNN4 (0.40) | KCNN4CES1MAPK1KIF11KCNH2 | |
| SCHEMBL10881157 | 0.76 | KCNN4 (0.39) | KCNN4CES1MAPK1KIF11KCNH2 | |
| SCHEMBL28022253 | 0.74 | KCNN4 (0.42) | KCNN4CES1MAPK1KDM4EALDH1A1 | |
| SCHEMBL9187550 | 0.74 | KCNN4 (0.41) | KCNN4CES1MAPK1KIF11KCNH2 | |
| Ammonia Solution, Strong SCHEMBL9395552 | 0.72 | KDM4E (0.32) | CES1MAPK1KIF11KCNH2KDM4E | |
| SCHEMBL5640704 | 0.72 | KCNN4 (0.39) | KCNN4CES1MAPK1KIF11KCNH2 | |
| SCHEMBL11808675 | 0.72 | KIF11 (0.46) | KCNN4KIF11KCNH2CYP2C19SMN1; SMN2 | |
| SCHEMBL15063659 | 0.72 | KCNN4 (0.44) | KCNN4CES1MAPK1KIF11KCNH2 | |
| SCHEMBL13931399 | 0.71 | KCNN4 (0.48) | KCNN4CES1MAPK1KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410048-B2 | Method for producing insulin analogs having a dibasic B chain terminus | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20090192073-A1 | METHOD FOR PRODUCING INSULIN ANALOGS HAVING A DIBASIC B CHAIN TERMINUS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192073-A1 | METHOD FOR PRODUCING INSULIN ANALOGS HAVING A DIBASIC B CHAIN TERMINUS | IAPP, IDE, INSR | KCNN4 1560/4885CES1 223/4885MAPK1 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.